Mathematical modelling human diseases and intervention strategies: HCV, SARS-CoV-2, and more.
Title: Mathematical modelling human diseases and intervention strategies: HCV, SARS-CoV-2, and more.
Presenter: Dr Pranesh Padmanabhan, QBI
Short abstract: Mathematical modelling has greatly enhanced our quantitative understanding of the pathogenesis and treatment of several acute and chronic viral infections. In this talk, I will delve into the insights gained from our work modelling viral infections. Specifically, I will describe our mathematical frameworks that have quantified the molecular determinants of hepatitis C virus (HCV) and SARS-CoV-2 virus entry into host cells, identified systems-level mechanisms underlying interferon-based HCV treatment failure, elucidated new drug synergy mechanisms, and examined the workings of COVID-19 vaccines.
Short bio: Pranesh Padmanabhan is a research fellow at the Queensland Brain Institute. His team combines mathematical modelling and quantitative imaging approaches to discover mechanisms underlying the progression of several infectious and neurodegenerative diseases and treatment outcomes.
About School research seminars
Seminars cover all aspects of chemistry and molecular biosciences and are delivered by visiting national and international academics. PhD completion seminars are also incorporated into the program.
Seminars are usually held in person and via zoom. All are welcome to attend.
Contacts
- Chemistry: Dr Rowan Young, Dr David Cantillo
- Molecular Biosciences: Dr Mathew Jones